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Radical surgery decreases overall morbidity and recurrence compared with conservative surgery for liver cystic echinococcosis: systematic review with meta-analysis

  
@article{ALES5402,
	author = {Chadli Dziri and Wejih Dougaz and Imen Samaali and Mehdi Khalfallah and Mhichem Jerraya and Ridha Mzabi and Ibtissem Bouasker and Ramzi Nouira and Abe Fingerhut},
	title = {Radical surgery decreases overall morbidity and recurrence compared with conservative surgery for liver cystic echinococcosis: systematic review with meta-analysis},
	journal = {Annals of Laparoscopic and Endoscopic Surgery},
	volume = {4},
	number = {0},
	year = {2019},
	keywords = {},
	abstract = {Background: This systematic review with meta-analysis aimed to investigate whether radical surgery (RS) for liver cystic echinococcosis (LCE) is superior to conservative surgery (CS) to decrease morbidity, mortality and recurrence.
Methods: MEDLINE, Embase, the Cochrane Library, Scopus, INIST, Ovid, Science Direct, Google Scholar, Springer link, clinical key, and web of science were searched up to April 13th, 2018. Adults of either sex operated on for symptomatic but non-complicated LCE were included. The quality of studies was assessed using the Jadad scoring system or the Methodological Index for Non-Randomized Studies index when appropriate. Meta-analyses were performed with a Mantel-Hansel method for random-effects.
Results: One randomized controlled trial, one retrospective comparative study using propensity-matching analysis for comparison and 14 retrospective comparative studies were included (3,771 patients). This meta-analysis showed that there were statistically significantly fewer biliary leakage +/− fistula [odds ratio (OR) =0.35; 95% CI, 0.21–0.60, P=0.00001], overall morbidity: (OR =0.49; 95% CI, 0.40–0.59, P=0.00001), and recurrence: (OR =0.17; 95% CI, 0.11–0.26; P},
	issn = {2518-6973},	url = {https://ales.amegroups.org/article/view/5402}
}