Complete mesocolic excision for colonic cancer: Society for Translational Medicine expert consensus statement

Minhua Zheng, Junjun Ma, Abe Fingerhut, Michel P. Adamina, Andrey Atroschenko, Roberto Bergamaschi, Mariana Berho, Luigi Boni, Sami Ahmed Chadi, William Tzu-Liang Chen, Conor P. Delaney, Giovanni Dapri, Igor E. Khatkov, Nam-Kyu Kim, Seon-Hahn Kim, Alexey Karachun, Davide Lomanto, Helen MacRae, Marco Milone, Mario Morino, Feza H. Remzi, Selman Uranues, Masahiko Watanabe, Steven Wexner


Total mesorectal excision (TME), a revolutionary change and a milestone in the history of surgical treatment for rectal cancer, has been widely recognized as the gold standard and is now a routine procedure. The concept of complete mesocolic excision (CME) was proposed based on the similar philosophy as TME, aimed to achieve better surgical quality and improve the oncological outcomes of colon cancer. In recent years, many surgeons have increasingly adopted the principle and conducted clinical trials to verify the effect of CME; however, whether CME should be used as the standard surgical technique is still controversial. In this article, we reviewed and updated the literature. Experts in this field from nine countries were invited to complete a questionnaire concerning CME, with the aim to illustrate the embryological and anatomical basis and reach a consensus of the current situation and future of CME.